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Chorionic villus sampling (CVS):
Indication and performance

Patient information - What should you know, what should you ask?

What is chorionic villus sampling?

A puncture of the chorion (at a later stage in pregnancy this is called the placenta) with the aim of obtaining and removing chorionic villi (cells) is called a chorionic villus sampling.

What is the indication for chorionic villus sampling?

  • Abnormal cDNA screening (non-invasive prenatal test).
  • Fetal malformations
  • Suspected fetal genetic disorders (including aneuploidies, microdeletion, microduplication)
  • Suspicion of metabolic diseases
  • thickened nuchal edema

How is the chorionic villus sampling performed?

Chorionic villus sampling is performed during ultrasound examination under sterile conditions. Beforehand, local anesthesia is applied through the abdominal wall.
The puncture is usually performed with a 1.2 mm diameter puncture needle.

When can the chorionic villus sampling be performed?

Chorionic villus sampling can be performed from 11+0 SSW.

What are the complications?

The complication rate is less than 0.2% for experienced fetal surgeons.
The most common complications include bleeding, amniotic fluid leakage, and injury.
Ultrasound monitoring is performed after the puncture.


Berlin Center for Prenatal Diagnostics and Fetal Surgery
MVZ Evangelisches Waldkrankenhaus

Prof. Dr. med. Michael Tchirikov

Specialist in obstetrics and gynecology
Focus: Special obstetrics and prenatal medicine

Consultation hours

Stadtrandstra├če 555
13589 Berlin

Mondays:8 am to 5 pm
Tuesdays:8 am to 5 pm
Wednesdays:Surgery day in the EWK 8 am to 5 pm
Thursdays:8 am to 5 pm
Fridays:8 am to 12pm
Telephone: +49 (0)30 - 42206830200
* Legally insured and self-payer