What is chorionic villus sampling?
A puncture of the chorion (at a later stage in pregnancy this is called the placenta) with the aim of obtaining and removing chorionic villi (cells) is called a chorionic villus sampling.
What is the indication for chorionic villus sampling?
- Abnormal cDNA screening (non-invasive prenatal test).
- Fetal malformations
- Suspected fetal genetic disorders (including aneuploidies, microdeletion, microduplication)
- Suspicion of metabolic diseases
- thickened nuchal edema
How is the chorionic villus sampling performed?
Chorionic villus sampling is performed during ultrasound examination under sterile conditions. Beforehand, local anesthesia is applied through the abdominal wall.
The puncture is usually performed with a 1.2 mm diameter puncture needle.
When can the chorionic villus sampling be performed?
Chorionic villus sampling can be performed from 11+0 SSW.
What are the complications?
The complication rate is less than 0.2% for experienced fetal surgeons.
The most common complications include bleeding, amniotic fluid leakage, and injury.
Ultrasound monitoring is performed after the puncture.